磷酸化p53结合蛋白1抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化p53结合蛋白1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive 磷酸化p53结合蛋白1抗体sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

磷酸化p53结合蛋白1抗体Also known as:

p53BP1 (Phospho-Ser1778); 53BP1 (Phospho-S1778); phospho-p53BP1(S1778); P-53BP1 (Ser1778); 53 BP1; FLJ41424; MGC138366; p202; p53 binding protein 1; p53 BP1; p53BP1; TP53 BP1; TP53BP1; Tumor protein 53 binding protein 1; Tumor protein p53 binding protein 1; Tumor suppressor p53 binding protein 1; TP53B_HUMAN; tumor protein 53-binding protein, 1.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化p53结合蛋白1抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Horse, Rabbit, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser1778.

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磷酸化p53结合蛋白1抗体Predicted Molecular Weight: 213kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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