睾丸特异性核苷酸果糖β抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 睾丸特异性核苷酸果糖β抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Polyadenylation of the 3-prime ends of eukaryotic mRNAs is a key event that takes place in the nucleus during maturation of mRNA. The reaction includes endoribonucleolytic cleavage of the pre-RNA at the poly(A) site that leads to synthesis of the poly(A) tail at the 3-prime end of the upstream cleavage product. The poly(A) polymerase (PAP) 睾丸特异性核苷酸果糖β抗体is required The adenosine addition reaction depends on poly(A) polymerase (PAP) activity. The testis express PAP-Beta (TPAP) in the cytoplasm of spermatogenic cells. The adenosine addition function of PAP-Beta plays a critical role in male germ cell production. PAP-Beta-deficient睾丸特异性核苷酸果糖β抗体 transgenic mice display impaired expression of haploid-specific genes that are necessary for spermatogenesis. The intronless gene encoding human PAP-∫ maps to chromosome 7p22.3.

Also known as:

PAP beta; PAP-beta; PAPT; poly(A) polymerase beta (testis specific); poly(A) polymerase beta; polynucleotide adenylyltransferase beta; TPAP.

Specificity:

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Rabbit Polyclonal IgG, 睾丸特异性核苷酸果糖β抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human PAPOLB.

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睾丸特异性核苷酸果糖β抗体Predicted Molecular Weight: 72kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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