神经细胞突触蛋白PCLO抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 神经细胞突触蛋白PCLO抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Piccolo is 1 component of the presynaptic cytomatrix. Bassoon is a large protein which is also found in the presynaptic compartments of rat brain synapses. Bassoon, along with Piccolo, is part of the ensemble of presynaptic proteins that are involved in orchestrating events at the nerve terminal. Bassoon is found in axon terminals of hippocampal neurons where it is highly concentrated in the vicinity of the active zone. Piccolo has a神经细胞突触蛋白PCLO抗体 similar distribution and colocalizes with Bassoon in cultured hippocampal cells. Piccolo zinc fingers interact with the dual prenylated rab3A and VAMP2/ Synaptobrevin II receptor PRA. Bassoon may be involved in cytomatrix organization at the site of neurotransmitter release. The gene which encodes bassoon maps to human chromosome 3p21.31. The gene which encodes piccolo maps to human chromosome 7q21.11.

神经细胞突触蛋白PCLO抗体Also known as:

ACZ; Aczonin; Brain-derived HLMN protein; DKFZp779G1236; KIAA0559; Multidomain presynaptic cytomatrix protein; PCLO; PCLO_HUMAN; Piccolo (presynaptic cytomatrix protein); Piccolo, mouse, homolog of antibody Pico; Presynaptic cytomatrix protein; Protein piccolo.

Specificity:

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Rabbit Polyclonal IgG,神经细胞突触蛋白PCLO抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, .

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Immunogen: KLH conjugated synthetic peptide derived from human Piccolo.

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Predicted Molecular Weight: 557kDa.

神经细胞突触蛋白PCLO抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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