G蛋白偶联嘌呤受体p2y9抗体

Quantity size:

0.2ml

Concentration:

1mg/ml G蛋白偶联嘌呤受体p2y9抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Nucleotides are emerging as important extracellular signaling molecules that mediate several effects, such as proliferation, differentiation , chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, P2X and P2Y. The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response G蛋白偶联嘌呤受体p2y9抗体to extracellular ATP. The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y9 is activated by lysophosphatidic acid (LPA), a lipid mediator involved in cell proliferation, differentiation, survival and death. In hamsters, P2Y9 mRNA G蛋白偶联嘌呤受体p2y9抗体is significantly expressed in ovary tissue compared to other tissues, and innervation with 1-oleoly LPA increases intracellular calcium ion concentration and stimulates adenylyl cyclase activity. P2Y9 is structurally related to nucleotide receptors, and shares 20-24% amino acid homology with the three other LPA receptors (LPA1, LPA2, LPA3).

G蛋白偶联嘌呤受体p2y9抗体Also known as:

5730485F04Rik; G protein coupled receptor 23; G-protein coupled receptor 23; GPR23; LPA receptor 4; LPA-4; LPA4; Lpar4; LPAR4_HUMAN; Lysophosphatidic acid receptor 4; Lysophosphatidic Acid Receptor P2Y9; P2RY9; P2Y purinoceptor 9; P2Y5 like; P2Y5-like receptor; P2Y9; Purinergic receptor 9.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human P2Y9.

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G蛋白偶联嘌呤受体p2y9抗体Predicted Molecular Weight: 42kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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