白细胞蛋白酶3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 白细胞蛋白酶3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The major features of Wegener granulomatosis are necrotizing granulomatous lesions, which most often affect the upper and lower airways and are associated with vasculitis, necrotizing glomerulonephritis and pulmonary capillaritis. The antigen responsible for this disease is Proteinase 3 (PR3, P29 or myeloblastin), which is one of the antibiotic proteins of neutrophilic granules belonging to the serine protease family. It is closely related to two others: Neutrophil Elastase and azurocidin. All three genes are expressed coordinately and their protein products are packaged together into 白细胞蛋白酶3抗体azurophil granules during neutrophil differentiation. PR3 is a neutrophil protein which is able to cleave elastin and is involved in proliferation of human leukemia cells. PR3 is expressed specifically in immature myeloid cells and is a G-CSF-responsive protein critical to factor-independent growth. The genes for all three of the related serine protease family members are located in a cluster on the tip of the short arm of human chromosome 19.

白细胞蛋白酶3抗体Also known as:

ACPA; AGP 7; AGP7; AGP7 serine proteinase; Azurophil Granule Protein 7; C ANCA antigen; C-ANCA antigen; EC 3.4.21.76; Leukocyte proteinase 3; MBN; MBT WEGENER AUTOANTIGEN; Myeloblastin; Neutrophil proteinase 4; NP 4; NP-4; NP4; P29; PR 3; PR-3; PR3; Proteinase3; PRTN 3; Prtn3; PRTN3_HUMAN; Serine proteinase neutrophil Wegener granulomatosis autoantigen; Wegener autoantigen.

Specificity:

●

Rabbit Polyclonal IgG,白细胞蛋白酶3抗体 affinity purified by Protein A.

●

Reacts with: Human, .

●

Immunogen: KLH conjugated synthetic peptide derived from human PR3.

●

Predicted Molecular Weight: 28kDa.

白细胞蛋白酶3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl949Ra01转化生长因子β3(TGFβ3)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 3 (TGFb3)

kl218Hu01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl218Mu01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl218Ra01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl124Hu01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Mu01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Ra01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Gu01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Rb51转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Ca01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Bo01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Po01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Cp01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Eq01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl124Ga01转化生长因子β1(TGFβ1)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1)

kl765Hu01精氨酸加压素诱导蛋白1(AVPI1)多克隆抗体Polyclonal Antibody to Arginine Vasopressin Induced Protein 1 (AVPI1)

kl765Mu01精氨酸加压素诱导蛋白1(AVPI1)多克隆抗体Polyclonal Antibody to Arginine Vasopressin Induced Protein 1 (AVPI1)

kl765Ra01精氨酸加压素诱导蛋白1(AVPI1)多克隆抗体Polyclonal Antibody to Arginine Vasopressin Induced Protein 1 (AVPI1)

kl312Hu01血管紧张素Ⅲ(AngⅢ)多克隆抗体Polyclonal Antibody to Angiotensin III (AngIII)

kl005Hu01血管紧张素Ⅱ(ANGⅡ)多克隆抗体Polyclonal Antibody to Angiotensin II (AngII)

kl851Ge01多巴胺(DA)多克隆抗体Polyclonal Antibody to Dokline (DA)

kl455Ge01雌三醇(E3)多克隆抗体Polyclonal Antibody to Estriol (E3)

kl461Ge01雌二醇(E2)多克隆抗体Polyclonal Antibody to Estradiol (E2)