磷酸化磷脂酰肌醇激酶调节亚单位gamma抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  磷酸化磷脂酰肌醇激酶调节亚单位gamma抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor磷酸化磷脂酰肌醇激酶调节亚单位gamma抗体 molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

磷酸化磷脂酰肌醇激酶调节亚单位gamma抗体Also known as:

phospho-PI 3 Kinase p55 gamma (Tyr199); PI 3 Kinase p55 gamma (phospho Y199); PIK3R3; PI3-kinase regulatory subunit gamma (phospho Tyr199); P55G_HUMAN; Phosphatidylinositol 3-kinase regulatory subunit gamma; PI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase 磷酸化磷脂酰肌醇激酶调节亚单位gamma抗体regulatory subunit p55-gamma; p55PIK; p55; p55-GAMMA; phosphoinositide-3-kinase, regulatory subunit 3 (gamma).

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human phospho-PI3-kinase regulatory subunit gamma (Tyr199).

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磷酸化磷脂酰肌醇激酶调节亚单位gamma抗体Predicted Molecular Weight: 54kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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