蛋白酶激活PA200抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 蛋白酶激活PA200抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

PA200 is a 1,843 amino acid nuclear protein that contains six HEAT (Huntington, Elongation Factor 3, PR65/A, TOR) repeats, which are conserved residues that form the hydrophobic domain core and are usually found in proteins that are involved in intracellular transport. Existing as a homodimer, PA200 interacts with the 20S and 26S proteasomes and activates proteasomal cleavage of peptides in an energy-independent manner. PA200 and 蛋白酶激活PA200抗体proteasomes function together within cells and respond to specific radiation-induced damage independent of the stage of cell cycle arrest. Broadly expressed, PA200 may also be involved in spermatogenesis and in DNA repair double-strand breaks (DSBs). Four isoforms of PA200 exists due to alternative splicing events.

蛋白酶激活PA200抗体Also known as:

Proteasome Activator Subunit 4; KIAA0077; PA200; Proteasome Activator 200 kDa; Proteasome activator complex subunit 4; Proteasome activator PA200; PSME 4; PSME4; PSME4_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse,蛋白酶激活PA200抗体 Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human PA200.

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Predicted Molecular Weight: 211kDa.

Storage:

蛋白酶激活PA200抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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