发育和分化增强因子PAG3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 发育和分化增强因子PAG3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein 发育和分化增强因子PAG3抗体forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate发育和分化增强因子PAG3抗体 and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Also known as:

AMAP 2; AMAP2; ANK repeat and PH domain-containing protein 2; Arf-GAP with SH3 domain; ASAP2; ASAP2_HUMAN; centaurin, beta 3; CENTB3; DDEF 2; DDEF2; Development and differentiation enhancing factor 2; Development and differentiation-enhancing factor 2; FLJ42910; KIAA0400;发育和分化增强因子PAG3抗体 PAG 3; PAG3; Pap alpha; PAP; Paxillin associated protein with ARFGAP activity 3; Paxillin-associated protein with ARF GAP activity 3; Pyk2 C terminus associated protein; Pyk2 C-terminus-associated protein; SHAG 1; SHAG1.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, .

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Immunogen: KLH conjugated synthetic peptide derived from human PAG3.

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Predicted Molecular Weight: 107kDa.

发育和分化增强因子PAG3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl004Mu01血管紧张素转化酶(ACE)多克隆抗体Polyclonal Antibody to Angiotensin I Converting Enzyme (ACE)

kl004Po01血管紧张素转化酶(ACE)多克隆抗体Polyclonal Antibody to Angiotensin I Converting Enzyme (ACE)

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kl006Ga01双调蛋白(AREG)多克隆抗体Polyclonal Antibody to Amphiregulin (AREG)

kl006Hu01双调蛋白(AREG)多克隆抗体Polyclonal Antibody to Amphiregulin (AREG)

kl006Mu01双调蛋白(AREG)多克隆抗体Polyclonal Antibody to Amphiregulin (AREG)

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kl006Ra01双调蛋白(AREG)多克隆抗体Polyclonal Antibody to Amphiregulin (AREG)

kl006Rb51双调蛋白(AREG)多克隆抗体Polyclonal Antibody to Amphiregulin (AREG)

kl007Bo01血管生长素(ANG)多克隆抗体Polyclonal Antibody to Angiogenin (ANG)

kl007Eq01血管生长素(ANG)多克隆抗体Polyclonal Antibody to Angiogenin (ANG)

kl007Hu01血管生长素(ANG)多克隆抗体Polyclonal Antibody to Angiogenin (ANG)

kl007Mu01血管生长素(ANG)多克隆抗体Polyclonal Antibody to Angiogenin (ANG)

kl007Po01血管生长素(ANG)多克隆抗体Polyclonal Antibody to Angiogenin (ANG)

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