丙酮酸脱氢酶激酶同功酶3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 丙酮酸脱氢酶激酶同功酶3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation丙酮酸脱氢酶激酶同功酶3抗体 cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

丙酮酸脱氢酶激酶同功酶3抗体Also known as:

[Pyruvate dehydrogenase [lipoamide] kinase isozyme 3 mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3; CMTX6; GS1-358P8.4; mitochondrial; PDK3; PDK3_HUMAN; Pyruvate dehydrogenase kinase isoenzyme 3; Pyruvate dehydrogenase kinase isoform 3; Pyruvate dehydrogenase kinase isozyme 3; Pyruvate dehydrogenase lipoamide kinase isozyme 3 mitochondrial.

Specificity:

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Rabbit Polyclonal IgG,丙酮酸脱氢酶激酶同功酶3抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human PDK3.

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Predicted Molecular Weight: 47kDa.

丙酮酸脱氢酶激酶同功酶3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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