磷酸化蛋白激酶Cη抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化蛋白激酶Cη抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific 磷酸化蛋白激酶Cη抗体expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte磷酸化蛋白激酶Cη抗体 differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq, Jul 2008]

Also known as:

PKC eta (phospho T656); p-PKC eta (phospho T656); KPCL_HUMAN; MGC 5363; MGC 5363; MGC26269; MGC5363; nPKC eta; nPKC-eta; PKC h; PKC L; PKC-L; PKCh; PKCL; PRKCH; PRKCL; Protein kinase 磷酸化蛋白激酶Cη抗体C eta; Protein kinase C eta type.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human PKC eta 磷酸化蛋白激酶Cη抗体around the phosphorylation site of Thr656.

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Predicted Molecular Weight: 80kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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