细胞膜钙ATP酶4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml细胞膜钙ATP酶4抗体   Buffer = Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Background:

Plasma membrane-type Ca2+-ATPases (PMCAs) mediate the export of bivalent calcium ions from eukaryotic cells. As members of the P class of ion-motive ATPases, PMCAs are a functionally diverse group of proteins that are derived from alternatively spliced transcripts originating from four distinct genes, PMCA1, 2, 3, and 4. The expression of different PMCA isoforms and splice variants is regulated in a developmental, tissue- and cell细胞膜钙ATP酶4抗体 type-specific manner, and with respect to the physiological needs of specific cell and tissue types. Spatial and temporal rates of resting intracellular Ca2+ concentrations and Ca2+ signaling in eukaryotic cells are dependent on the array of PMCA isoforms that are expressed in concert with the rate of Ca2+ export. PMCA3 expression is confined to brain and skeletal muscle. The PMCA4 gene is located on human chromosome 1q25 and is ubiquitously expressed.

细胞膜钙ATP酶4抗体Also known as:

MXRA 1; MXRA1; Plasma membrane calcium ATPase 4; Plasma membrane calcium ATPase isoform 4; Plasma membrane calcium pump isoform 4; Plasma membrane calcium transporting ATPase 4; Plasma membrane calcium-transporting ATPase 4; PMCA 4; PMCA4; PMCA-4; PMCA4b; PMCA4x; Sarcolemmal calcium pump; AT2B4_HUMAN; ATP2B2; ATP2B4; ATPase Ca++ transporting plasma membrane 4; DKFZp686G08106; DKFZp686M088; Matrix remodelling associated 1; Matrix remodelling associated protein 1; Matrix-remodeling-associated protein 1

Specificity:

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Rabbit Polyclonal IgG,细胞膜钙ATP酶4抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human PMCA4.

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Predicted Molecular Weight: 138kDa.

细胞膜钙ATP酶4抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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