喹啉酸磷酸核糖基转移酶抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 喹啉酸磷酸核糖基转移酶抗体  Buffer = Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Background:

Quinolinate phosphoribosyltransferase (QPRTase) is a major enzyme in the catabolism of quinolinate. Quinolinate is an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide, and pyrophosphate. Catabolism of quinolinate is vital due to the quinolinate’s neurotoxicity.  喹啉酸磷酸核糖基转移酶抗体Increased levels of quinolinate have been linked to neurodegenerative symptoms associated with meningitis and AIDS. QAPRTase has a seven-stranded alpha/beta-barrel domain which is similar in structure to the eight-stranded alpha/beta-barrel enzymes. The protein possesses a novel fold in comparison to other members of the PRTase family. This fold comprises a structure combining two domains. The structure is part alpha/beta barrel-like domain, and part alpha/beta N-terminal domain.

 喹啉酸磷酸核糖基转移酶抗体Also known as:

NADC_HUMAN; Nicotinate nucleotide pyrophosphorylase (carboxylating); Nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; QPRT; QPRTase; Quinolinate phosphoribosyltransferase [decarboxylating]; Quinolinate phosphoribosyltransferase.

Specificity:

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Rabbit Polyclonal IgG,  喹啉酸磷酸核糖基转移酶抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human QPRT/QAPRTase .

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Predicted Molecular Weight: 31kDa.

Storage:

 喹啉酸磷酸核糖基转移酶抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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