Ras蛋白脑组织同源类似物RHEB蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml Ras蛋白脑组织同源类似物RHEB蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor Ras蛋白脑组织同源类似物RHEB蛋白抗体stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demon-strate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing theRas蛋白脑组织同源类似物RHEB蛋白抗体 availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.

Also known as:

GTP-binding protein Rheb; MGC111559; Ras homolog enriched in brain 2; Ras homolog enriched in brain; RHEB 2; RHEB-2 RHEB2; RHEB_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,Ras蛋白脑组织同源类似物RHEB蛋白抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Cow, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human RHEB.

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Predicted Molecular Weight: 20kDa.

Ras蛋白脑组织同源类似物RHEB蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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