ras癌基因家族Rab8蛋白/原癌基因c MEL抗体

Quantity size:

0.2ml

Concentration:

1mg/ml ras癌基因家族Rab8蛋白/原癌基因c MEL抗体Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4ras癌基因家族Rab8蛋白/原癌基因c MEL抗体 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

ras癌基因家族Rab8蛋白/原癌基因c MEL抗体Also known as:

MEL; Mel transforming oncogene; Oncogene c mel; Oncogene c-mel; RAB8; RAB8A; RAB8A member RAS oncogene family; RAB8A_HUMAN; Ras associated protein RAB8; Ras related protein Rab 8A; Ras-related protein Rab-8A.

Specificity:

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Rabbit Polyclonal IgG,ras癌基因家族Rab8蛋白/原癌基因c MEL抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human RAB8A.

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Predicted Molecular Weight: 23kDa.

ras癌基因家族Rab8蛋白/原癌基因c MEL抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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