环指蛋白47抗体

参考价:面议
供货周期: 现货
品牌: 康朗生物
规格: 0.1ml/0.2ml
货号: KL6320R
CAS号:
上海康朗生物科技有限公司
银牌会员9年生产商
关注展位 全部试剂
产品详情

Quantity size:

0.2ml

Concentration:

1mg/ml  环指蛋白47抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Two converging apoptotic pathways, which are initiated either through the activation of death domain (DD) receptors by an extrinsic pathway or by an intrinsic pathway in the mitochondria, mediate the activation and progression of apoptosis within the cell. Both these pathways lead to the activation of the Serine proteinase cascade (caspases) and to环指蛋白47抗体 cleavage of these pro-caspases. A novel protein, BAR, for bifunctional apoptosis regulator, contains domains that enable it to interact with components of both major apoptosis pathways, where it negatively regulates apoptotic signaling. Like the other anti-apoptosis proteins Bap31 and FLIP, BAR contains a DED-like domain that is capable of suppressing apoptosis mediated at环指蛋白47抗体 the receptor level. In addition, BAR contains a domain that also enables it to interact with the mitochondrial Bcl-2 family of proteins. The presence of these various RING, SAM, DED and TM domains suggests that BAR may serve as a scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery.

环指蛋白47抗体Also known as:

BAR; Bfar; BFAR_HUMAN; Bifunctional apoptosis inhibitor; Bifunctional apoptosis regulator; RING finger protein 47; RNF47.

Specificity:

Rabbit Polyclonal IgG, affinity purified by Protein A.

Reacts with: Human, Mouse, Rat, .

Immunogen: KLH conjugated synthetic peptide derived from human Bifunctional apoptosis inhibitor.

环指蛋白47抗体Predicted Molecular Weight: 53kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl440Hu01整合素β4(ITGβ4)多克隆抗体Polyclonal Antibody to Integrin Beta 4 (ITGb4)

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