原癌基因R-Ras抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  原癌基因R-Ras抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

H-Ras, K-Ras and N-Ras represent the prototype members of a family of small G proteins that are frequently activated to an oncogenic state in a wide variety of human tumors. Activation is due to point mutations at either position 12 or 61 within their coding sequence. Such mutations cause these proteins to be constitutively converted to原癌基因R-Ras抗体 their active, rather than the inactive, GDP-bound state. The related human R-Ras gene was initially cloned by low stringency hybridization methods. The R-Ras protein has been shown to interact with the Bcl-2 gene product involved in a signaling pathway that intervenes with apoptosis. Positions 38 and 87 (analogous to positions 12 and 61 in H-Ras) mutants of R-Ras have been shown to be capable of activating oncogenic function. Data has been obtained indicating原癌基因R-Ras抗体 that R-Ras may exert its biological effect by means of modulating the activity of the Raf-1 kinase on its direct downstream effectors.

Also known as:

Oncogene RRAS; p23; R Ras; Ras related Protein; Ras related protein R Ras; Ras-related protein R-Ras; related RAS viral (r ras) oncogene homolog; RRAS; RRAS_HUMAN.

原癌基因R-Ras抗体Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, .

●

Immunogen: KLH conjugated synthetic peptide derived from human RRAS (152-190aa).

●

Predicted Molecular Weight: 23kDa.

原癌基因R-Ras抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

l637Hu01转化生长因子β刺激蛋白22(TSC22)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta Stimulated Protein Clone 22 (TSC22)

kl638Ra01白介素10受体β(IL10Rβ)多克隆抗体Polyclonal Antibody to Interleukin 10 Receptor Beta (IL10Rb)

kl640Hu01前列腺素D合酶(PTGDS)多克隆抗体Polyclonal Antibody to Prostaglandin D2 Synthase, Hematopoietic (PTGDS)

kl643Mu01白介素13受体α2(IL13Rα2)多克隆抗体Polyclonal Antibody to Interleukin 13 Receptor Alpha 2 (IL13Ra2)

kl646Hu01黑素瘤衍生亮氨酸拉链额外核因子(MLZE)多克隆抗体Polyclonal Antibody to Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE)

kl647Hu01趋化因子C-C-基元受体7(CCR7)多克隆抗体Polyclonal Antibody to Chemokine C-C-Motif Receptor 7 (CCR7)

kl647Mu01趋化因子C-C-基元受体7(CCR7)多克隆抗体Polyclonal Antibody to Chemokine C-C-Motif Receptor 7 (CCR7)

kl649Hu01钾氯协同转运蛋白2(KCC2)多克隆抗体Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2)

kl651Hu01皮肤T-细胞虏获趋化因子(CTACK)多克隆抗体Polyclonal Antibody to Cutaneous T-Cell Attracting Chemokine (CTACK)

kl652Hu01白介素18受体1(IL18R1)多克隆抗体Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1)

kl653Ga01肌肉生长抑制素(MSTN)多克隆抗体Polyclonal Antibody to Myostatin (MSTN)

kl653Hu01肌肉生长抑制素(MSTN)多克隆抗体Polyclonal Antibody to Myostatin (MSTN)

kl653Mu01肌肉生长抑制素(MSTN)多克隆抗体Polyclonal Antibody to Myostatin (MSTN)

kl653Ra01肌肉生长抑制素(MSTN)多克隆抗体Polyclonal Antibody to Myostatin (MSTN)

kl655Hu01白介素18受体辅助蛋白(IL18RAP)多克隆抗体Polyclonal Antibody to Interleukin 18 Receptor Accessory Protein (IL18RAP)

kl657Ra01肉毒碱脂酰转移酶(CACT)多克隆抗体Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT)

kl658Hu01血管紧张素Ⅱ受体1(AGTR1)多克隆抗体Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1)

kl658Ra01血管紧张素Ⅱ受体1(AGTR1)多克隆抗体Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1)

kl659Hu01胰岛素样生长因子1受体(IGF1R)多克隆抗体Polyclonal Antibody to Insulin Like Growth Factor 1 Receptor (IGF1R)

kl660Hu01脂肪酸转运蛋白5(FATP5)多克隆抗体Polyclonal Antibody to Fatty Acid Transport Protein 5 (FATP5)

kl667Hu01肌联蛋白(TTN)多克隆抗体Polyclonal Antibody to Titin (TTN)