RAN结合蛋白2/核孔蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml RAN结合蛋白2/核孔蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The nuclear pore complex protein, Ran-binding protein 2 (Ran BP-2 or Nup358), contains four Ran-binding domains. Ran BP-2 is a large scaffold cyclophilin-related protein expressed in photoreceptor cells. Ran BP-2 localization at cytoplasmic fibrils emanating from the nuclear pore complex and interaction with the Ran-GTPase support its role in nucleocytoplasmicRAN结合蛋白2/核孔蛋白抗体 transport processes. In humans, the Ran BP-2 gene is partially duplicated in a gene cluster and lies in a hot spot for recombination on chromosome 2q. This genetic heterogeneity RAN结合蛋白2/核孔蛋白抗体renders further significance of this genomic region in human disease due to its possible involvement in genetically linked disorders such as juvenile nephronophthisis, congenital hepatic fibrosis and chorioretinal dysplasia.

Also known as:

Nuclear pore complex protein Nup358; Nucleoporin 358; Nucleoporin Nup358; NUP358; P270; RAN binding protein 2; RAN结合蛋白2/核孔蛋白抗体Ran-binding protein 2; RANBP2; RBP2_HUMAN; Transformation related protein 2; TRP 1; TRP 2; TRP1; TRP2; 358 kDa nucleoporin; E3 SUMO-protein ligase RanBP2.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Cow, .

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Immunogen: KLH conjugated synthetic peptide derived from human RanBP2.

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RAN结合蛋白2/核孔蛋白抗体Predicted Molecular Weight: 355kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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