供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL11476R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 轴突导向受体蛋白3抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin 轴突导向受体蛋白3抗体(Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain. Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS); an autosomal 轴突导向受体蛋白3抗体recessive disorder characterized by congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla. Alternative transcript variants have been described but have not been experimentally validated.
轴突导向受体蛋白3抗体Also known as:
HGPPS; HGPS; RB inhibiting gene 1; Rbig 1; Rbig1; Retinoblastoma inhibiting gene 1; Rig 1; Rig1; Robo 3; Robo3; Robo3 protein; ROBO3_HUMAN; Roundabout axon guidance receptor homolog 3; Roundabout homolog 3; Roundabout like protein 3; Roundabout, axon guidance receptor, homolog 3 (Drosophila); Roundabout-like protein 3.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Robo3.
●
轴突导向受体蛋白3抗体Predicted Molecular Weight: 146kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
IHC-P=1:100-500 IHC-F=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user
kl799Mu01骨成型蛋白7(BMP7)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 7 (BMP7)
kl799Ra01骨成型蛋白7(BMP7)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 7 (BMP7)
kl800Hu01妊娠关联血浆蛋白A(klPA)多克隆抗体Polyclonal Antibody to Pregnancy Associated Plasma Protein A (klPA)
kl800Mu01妊娠关联血浆蛋白A(klPA)多克隆抗体Polyclonal Antibody to Pregnancy Associated Plasma Protein A (klPA)
kl801Hu01碱性鞘磷脂磷酸二酯酶(Alk-Smase)多克隆抗体Polyclonal Antibody to Alkaline Sphingomyelinase (Alk-Smase)
kl801Mu01碱性鞘磷脂磷酸二酯酶(Alk-Smase)多克隆抗体Polyclonal Antibody to Alkaline Sphingomyelinase (Alk-Smase)
kl801Ra01碱性鞘磷脂磷酸二酯酶(Alk-Smase)多克隆抗体Polyclonal Antibody to Alkaline Sphingomyelinase (Alk-Smase)
kl802Hu01胆囊收缩素(CCK)多克隆抗体Polyclonal Antibody to Cholecystokinin (CCK)
kl802Mu01胆囊收缩素(CCK)多克隆抗体Polyclonal Antibody to Cholecystokinin (CCK)
kl802Po01胆囊收缩素(CCK)多克隆抗体Polyclonal Antibody to Cholecystokinin (CCK)
kl802Ra01胆囊收缩素(CCK)多克隆抗体Polyclonal Antibody to Cholecystokinin (CCK)
kl803Hu01神经介素B(NMB)多克隆抗体Polyclonal Antibody to Neuromedin B (NMB)
kl803Mu01神经介素B(NMB)多克隆抗体Polyclonal Antibody to Neuromedin B (NMB)
kl807Hu01岩藻糖苷酶αL1(FUCα1)多克隆抗体Polyclonal Antibody to Fucosidase Alpha L1, Tissue (FUCa1)
kl810Hu01心肌营养素1(CT1)多克隆抗体Polyclonal Antibody to Cardiotrophin 1 (CT1)
kl810Mu01心肌营养素1(CT1)多克隆抗体Polyclonal Antibody to Cardiotrophin 1 (CT1)
kl810Ra01心肌营养素1(CT1)多克隆抗体Polyclonal Antibody to Cardiotrophin 1 (CT1)
kl814Hu01脂质转运蛋白(CETP)多克隆抗体Polyclonal Antibody to Cholesteryl Ester Transfer Protein (CETP)
kl814Rb52脂质转运蛋白(CETP)多克隆抗体Polyclonal Antibody to Cholesteryl Ester Transfer Protein (CETP)
kl815Hu01神经型一氧化氮合酶(NOS1)多克隆抗体Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)
kl815Ra01神经型一氧化氮合酶(NOS1)多克隆抗体Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)
kl817Bo01结合珠蛋白(Hpt)多克隆抗体Polyclonal Antibody to Haptoglobin (Hpt)
kl817Po01结合珠蛋白(Hpt)多克隆抗体Polyclonal Antibody to Haptoglobin (Hpt)
相关产品
关注
拨打电话
留言咨询