Rho GTP酶激活蛋白1/血管畸形骨肥大综合征相关蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  Rho GTP酶激活蛋白1/血管畸形骨肥大综合征相关蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their Rho GTP酶激活蛋白1/血管畸形骨肥大综合征相关蛋白抗体excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).

Rho GTP酶激活蛋白1/血管畸形骨肥大综合征相关蛋白抗体Also known as:

Ras GAP; CM AVM; CMAVM; DKFZp434N071; GAP; GTPase activating protein; GTPase-activating protein; OTTHUMP00000222390; OTTHUMP00000222391; OTTHUMP00000222392; OTTHUMP00000222393; p120GAP; p120RASGAP; PKWS; Ras GTPase-activating protein 1; GTPase-activating protein; RAS p21 protein activator (GTPase activating protein) 1; Ras p21 protein activator;Rho GTP酶激活蛋白1/血管畸形骨肥大综合征相关蛋白抗体 RASA; RASA1; RASA1_HUMAN; RasGAP; Triphosphatase activating protein.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, .

●

Immunogen: KLH conjugated synthetic peptide derived from human Ras GTPase-activating protein 1.

●

Rho GTP酶激活蛋白1/血管畸形骨肥大综合征相关蛋白抗体Predicted Molecular Weight: 116kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

l995Ra01血幼素(HJV)多克隆抗体Polyclonal Antibody to Hemojuvelin (HJV)

kl996Hu01载脂蛋白C2(APOC2)多克隆抗体Polyclonal Antibody to Apolipoprotein C2 (APOC2)

kl996Ra01载脂蛋白C2(APOC2)多克隆抗体Polyclonal Antibody to Apolipoprotein C2 (APOC2)

kl997Hu01载脂蛋白A5(APOA5)多克隆抗体Polyclonal Antibody to Apolipoprotein A5 (APOA5)

kl998Hu01KSP钙黏蛋白(CDH16)多克隆抗体Polyclonal Antibody to Cadherin 16 (CDH16)

kl999Hu01基质金属蛋白酶28(MMP28)多克隆抗体Polyclonal Antibody to Matrix Metalloproteinase 28 (MMP28)

kl000Hu01触珠蛋白相关蛋白(HPR)多克隆抗体Polyclonal Antibody to Haptoglobin Related Protein (HPR)

kl002Hu01肝肠钙黏蛋白(CDH17)多克隆抗体Polyclonal Antibody to Cadherin 17 (CDH17)

kl003Po01载脂蛋白B(APOB)多克隆抗体Polyclonal Antibody to Apolipoprotein B (APOB)

kl005Hu01大型中性氨基酸转运蛋白1(LAT1)多克隆抗体Polyclonal Antibody to Large Neutral Amino Acid Transporter 1 (LAT1)

kl006Ra01白介素8受体β(IL8Rβ)多克隆抗体Polyclonal Antibody to Interleukin 8 Receptor Beta (IL8Rb)

kl007Hu01白介素34(IL34)多克隆抗体Polyclonal Antibody to Interleukin 34 (IL34)

kl007Mu01白介素34(IL34)多克隆抗体Polyclonal Antibody to Interleukin 34 (IL34)

kl009Hu01S100钙结合蛋白A2(S100A2)多克隆抗体Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2)

kl010Hu01蛋白Z依赖性蛋白酶抑制因子(ZPI)多克隆抗体Polyclonal Antibody to Protein Z Dependent Protease Inhibitor (ZPI)

kl010Mu01蛋白Z依赖性蛋白酶抑制因子(ZPI)多克隆抗体Polyclonal Antibody to Protein Z Dependent Protease Inhibitor (ZPI)

kl010Ra01蛋白Z依赖性蛋白酶抑制因子(ZPI)多克隆抗体Polyclonal Antibody to Protein Z Dependent Protease Inhibitor (ZPI)

kl011Hu01补体因子B(CFB)多克隆抗体Polyclonal Antibody to Complement Factor B (CFB)

kl011Mu01补体因子B(CFB)多克隆抗体Polyclonal Antibody to Complement Factor B (CFB)

kl011Ra01补体因子B(CFB)多克隆抗体Polyclonal Antibody to Complement Factor B (CFB)

kl012Hu01二氢嘧啶脱氢酶(DPYD)多克隆抗体Polyclonal Antibody to Dihydropyrimidine Dehydrogenase (DPYD)

kl012Mu01二氢嘧啶脱氢酶(DPYD)多克隆抗体Polyclonal Antibody to Dihydropyrimidine Dehydrogenase (DPYD)

kl014Hu01趋化因子C-C-基元受体6(CCR6)多克隆抗体Polyclonal Antibody to Chemokine C-C-Motif Receptor 6 (CCR6)

kl019Hu01血小板激活因子乙酰水解酶2(klAH2)多克隆抗体Polyclonal Antibody to Platelet Activating Factor Acetylhydrolase 2 (klAH2)

kl020Ra01S100钙结合蛋白A4(S100A4)多克隆抗体Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4)

kl021Hu01S100钙结合蛋白A5(S100A5)多克隆抗体Polyclonal Antibody to S100 Calcium Binding Protein A5 (S100A5)