Ras蛋白特异鸟嘌呤核苷酸释放因子1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml Ras蛋白特异鸟嘌呤核苷酸释放因子1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of Ras蛋白特异鸟嘌呤核苷酸释放因子1抗体bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008].

Ras蛋白特异鸟嘌呤核苷酸释放因子1抗体Also known as:

Calcium and DAG-regulated guanine nucleotide exchange factor II; CALDAG-GEFI; CALDAG-GEFII; Guanine nucleotide exchange factor, calcium and DAG regulated, Rap1A; hRasGRP1; Ras activator RasGRP; RAS guanyl nucleotide releasing protein 1; RAS guanyl releasing protein 1 (calcium and DAG-regulated); RAS guanyl releasing protein 1; RASGRP; RASGRP1; Ras蛋白特异鸟嘌呤核苷酸释放因子1抗体GRP1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human Rasgrp1.

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Ras蛋白特异鸟嘌呤核苷酸释放因子1抗体Predicted Molecular Weight: 90kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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