磷酸化视网膜母细胞瘤相关蛋白p130抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化视网膜母细胞瘤相关蛋白p130抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and is known to regulate the activity of E2F 磷酸化视网膜母细胞瘤相关蛋白p130抗体transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.

磷酸化视网膜母细胞瘤相关蛋白p130抗体Also known as:

Rb2 p130 (phospho S952); p-Rb2 p130 (phospho S952); p130; PRB2; Rb2; RBL2; RBR2; Retinoblastoma like 2; Retinoblastoma like protein 2.

Specificity:

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Rabbit Polyclonal IgG,磷酸化视网膜母细胞瘤相关蛋白p130抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KKLH conjugated synthesised phosphopeptide derived from human Rb2 p130 around the phosphorylation site of Ser952.

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磷酸化视网膜母细胞瘤相关蛋白p130抗体Predicted Molecular Weight: 128kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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