感觉神经性耳聋常染色体隐性遗传61抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 感觉神经性耳聋常染色体隐性遗传61抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes 感觉神经性耳聋常染色体隐性遗传61抗体a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins.感觉神经性耳聋常染色体隐性遗传61抗体 Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]

Also known as:

Prestin; Deafness neurosensory autosomal recessive 61; DFNB 61; DFNB61; MGC118886; MGC118887; MGC118888; MGC118889; PRES; Prestin (motor protein); Prestin; S26A5_HUMAN; SLC26A5;感觉神经性耳聋常染色体隐性遗传61抗体 Solute carrier family 26 member 5 (prestin); Solute carrier family 26 member 5.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human Slc26a5.

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感觉神经性耳聋常染色体隐性遗传61抗体Predicted Molecular Weight: 81kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

IHC-P=1:100-500  IHC-F=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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