供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL11755R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 丝氨酸/苏氨酸蛋白激酶SRPK7抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns, and they are required for accurate splice site recognition and the control of alternative splicing (1). Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20, 丝氨酸/苏氨酸蛋白激酶SRPK7抗体and SF2/ASF (2). The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/serine (RS)-rich domain, and they are essential for constitutive splicing and also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites (3,4). The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20, and 9G8 are continuously 丝氨酸/苏氨酸蛋白激酶SRPK7抗体shuttled between the nucleus and the cytoplasm and contribute to mRNA transport (5). The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing-sites (6).
丝氨酸/苏氨酸蛋白激酶SRPK7抗体Also known as:
9G8; SRp20; AAG3; HSSG1; RBM37; Splicing factor 9G8; Splicing factor, arginine/serine rich 7; ZCCHC20; ZCRB2; SRSF7_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Cow, Zebrafish, .
●
Immunogen: KLH conjugated synthetic peptide derived from human SRp20 (2-70aa).
●
丝氨酸/苏氨酸蛋白激酶SRPK7抗体Predicted Molecular Weight: 27kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user
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