神经突触相关蛋白SLITRK2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  神经突触相关蛋白SLITRK2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich)神经突触相关蛋白SLITRK2抗体 repeats and is expressed in neural tissues, with highest levels found in adult cerebral cortex. Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, suggesting that it suppresses neurite outgrowth. Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth. Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia. There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events.

神经突触相关蛋白SLITRK2抗体Also known as:

CXorf2; KIAA1854; SLIK2_HUMAN; SLIT and NTRK like protein 2; SLIT and NTRK-like protein 2; SLITL1; SLITRK 2; Slitrk2.

Specificity:

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Rabbit Polyclonal IgG, 神经突触相关蛋白SLITRK2抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, .

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Immunogen: KLH conjugated synthetic peptide derived from human SLITRK2.

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神经突触相关蛋白SLITRK2抗体Predicted Molecular Weight: 93kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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