磷酸化丝裂原活化蛋白激酶磷酸酶p38γ抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化丝裂原活化蛋白激酶磷酸酶p38γ抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38 alpha, p38 beta and p38 gamma, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 磷酸化丝裂原活化蛋白激酶磷酸酶p38γ抗体proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38 alpha, p38 beta and p38 gamma are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.

磷酸化丝裂原活化蛋白激酶磷酸酶p38γ抗体Also known as:

p-SAPK3(phospho-Thr183+Tyr185); MAP kinase 12; MAP kinase p38 gamma; MAPK 12; Mapk12; Mitogen Activated Protein Kinase 12; ERK6; ERK 6; ERK-6; Extracellular signal-regulated kinase 6; Mitogen activated protein kinase 3; Mitogen activated protein kinase p38 gamma; Mitogen-activated protein kinase 12; Mitogen-activated protein kinase p38 gamma; 磷酸化丝裂原活化蛋白激酶磷酸酶p38γ抗体MK12_HUMAN; P38 GAMMA; P38GAMMA; PRKM12; SAPK 3; SAPK3; Stress Activated Protein Kinase 3; Stress-activated protein kinase 3.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Guinea Pig, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human SAPK3 around the phosphorylation site of Thr183+Tyr185 [EM(p-T)G(p-Y)VV].

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磷酸化丝裂原活化蛋白激酶磷酸酶p38γ抗体Predicted Molecular Weight: 42kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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