钠通道亚基β4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 钠通道亚基β4抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The SCN4B protein modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation By similarity. The protein has been found to be expressed at a high 钠通道亚基β4抗体level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. Defects in SCN4B are the cause of long QT syndrome type 10 (LQT10) [MIM:611819]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to 钠通道亚基β4抗体excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy.

Also known as:

SCN4B_HUMAN. Sodium channel subunit beta-4.

Specificity:

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Rabbit Polyclonal IgG,钠通道亚基β4抗体 affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthetic peptide derived from human SCN4B.

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Predicted Molecular Weight: 22kDa.

钠通道亚基β4抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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