ATP依赖解旋酶SMARCA2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml ATP依赖解旋酶SMARCA2抗体  Buffer = Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Background:

A transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 / BRM belongs to the SNF2/RAD54 helicase family, is a homologue of the Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma proteins. It contains a methyl lysine containing bromo domain and an HSA domain. The yeast protein SNF2, also known as SWI2, is involved in transcriptional activation of numerous genes. It contains a domain that is highly conserved among several known helicasesATP依赖解旋酶SMARCA2抗体 and is required for transcriptional activity. SNF2/SWI2 is highly homologous to the Drosophila protein 'brahma' (brm). Although the 2 proteins show nuclear localization during interphase, they are excluded from the condensed chromosomes during mitosis. They found that the level of BRM, but not BRG1, was strongly reduced during mitosis. Phosphorylation of hbrm and BRG1 did not disrupt their association with SNF5 but correlated with a decreased affinity for the nuclear structure in early M phase.

ATP依赖解旋酶SMARCA2抗体Also known as:

BRM; ATP dependent helicase SMARCA2; BAF190; BRM; Global transcription activator homologous sequence; hBRM; hSNF2a; Possible global transcription activator SNF2L2; SMARCA2; SMCA2_HUMAN; SNF2 alpha; SNF2 like 2; SNF2/SWI2 like protein 2; SNF2A; SNF2LA; Sth1p; Sucrose nonfermenting 2 like protein 2; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a member 2.

Specificity:

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Rabbit Polyclonal IgG,ATP依赖解旋酶SMARCA2抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human SMARCA2.

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Predicted Molecular Weight: 230kDa.

ATP依赖解旋酶SMARCA2抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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