供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL0100R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 转移生长因子β2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.
The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, 转移生长因子β2抗体 and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell 转移生长因子β2抗体 types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
Also known as:
BSC 1 cell growth inhibitor; BSC1 cell growth inhibitor; Cetermin; G TSF; Glioblastoma derived T cell suppressor; Glioblastoma derived T cell suppressor factor; GTSF; MGC116892; Polyergin; TGF B2; TGF beta2; TGFB 2; TGFB2; Transforming growth factor beta 2.TGF B2; BSC 1 cell growth inhibitor; BSC-1 cell growth inhibitor; BSC1 cell growth inhibitor; Cetermin; G TSF; G-TSF; Glioblastoma derived T cell suppressor; Glioblastoma 转移生长因子β2抗体 derived T cell suppressor factor; Glioblastoma-derived T-cell suppressor factor; GTSF; MGC116892; Polyergin; TGF beta2; TGF-beta-2; TGF-beta2; TGFB 2; TGFB2; TGFB2_HUMAN; Transforming growth factor beta 2; Transforming growth factor beta-2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human TGF-beta 2.
●
转移生长因子β2抗体 Predicted Molecular Weight: 12/45kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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