肥大细胞类胰蛋白酶β2

Quantity size:

0.2ml

Concentration:

1mg/ml  肥大细胞类胰蛋白酶β2 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3'肥大细胞类胰蛋白酶β2 UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the肥大细胞类胰蛋白酶β2 main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Also known as:

Tryptase beta-2; Tryptase-2; Tryptase II; TPS2; AV011504; Mcp-6; MCPT6; MMCP-6; TPS2; TPSB2; TRYPTASE 2;肥大细胞类胰蛋白酶β2 TRYPTASE BETA/II; tryptaseB; tryptaseC; tryptase beta-2 precursor; tryptase beta 2 (gene/pseudogene); TRYB1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from mouse TPSB2 (234-280aa).

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肥大细胞类胰蛋白酶β2Predicted Molecular Weight: 27kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl095Po01巨噬细胞炎性蛋白3α(MIP3α)多克隆抗体Polyclonal Antibody to Macrophage Inflammatory Protein 3 Alpha (MIP3a)

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