磷酸化NF-κB活化激酶抗体

Quantity size:

0.1ml

Concentration:

1mg/ml  磷酸化NF-κB活化激酶抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates Borna disease virus (BDV) P protein. Phosphorylates磷酸化NF-κB活化激酶抗体 and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response. Inhibition of its interaction with IRF3, due to HCV NS3 binding or BDV P protein seems to be one mechanism of inhibition of the innate immune responses of hepatitis C virus (HCV) infection or Borna disease virus infection respectively. Ubiquitous with higher expression in testis. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.

磷酸化NF-κB活化激酶抗体Also known as:

NAK (phospho S172); Phospho-TBK1/NAK (Ser172); P-TBK1(Ser172); p-NAK(Ser172); TRAF-associated NF-κB kinase; TANK protein; TANK-binding kinase 1; T2K; NF-kappa-B-activating kinase; Serine/threonine-protein kinase TBK1; I TRAF; ITRAF; TRAF family member associated NF KAPPA B activator; TRAF family member associated NFKB activator; TRAF interacting protein; TRAF interacting protein TANK isoform a; TRAF interacting protein 磷酸化NF-κB活化激酶抗体TANK isoform b; TRAF2.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, .

●

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human TBK1 around the phosphorylation site of Ser172.

●

磷酸化NF-κB活化激酶抗体Predicted Molecular Weight: 84kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl214Hu01窖蛋白(CAV1)多克隆抗体Polyclonal Antibody to Caveolin 1 (CAV1)

kl214Mu01窖蛋白(CAV1)多克隆抗体Polyclonal Antibody to Caveolin 1 (CAV1)

kl214Po01窖蛋白(CAV1)多克隆抗体Polyclonal Antibody to Caveolin 1 (CAV1)

kl214Ra01窖蛋白(CAV1)多克隆抗体Polyclonal Antibody to Caveolin 1 (CAV1)

kl214Rb51窖蛋白(CAV1)多克隆抗体Polyclonal Antibody to Caveolin 1 (CAV1)

kl214Si01窖蛋白(CAV1)多克隆抗体Polyclonal Antibody to Caveolin 1 (CAV1)

kl215Bo01Ⅰ型胶原α2(COL1α2)多克隆抗体Polyclonal Antibody to Collagen Type I Alpha 2 (COL1a2)

kl215Ca01Ⅰ型胶原α2(COL1α2)多克隆抗体Polyclonal Antibody to Collagen Type I Alpha 2 (COL1a2)

kl215Ga01Ⅰ型胶原α2(COL1α2)多克隆抗体Polyclonal Antibody to Collagen Type I Alpha 2 (COL1a2)

kl215Hu01Ⅰ型胶原α2(COL1α2)多克隆抗体Polyclonal Antibody to Collagen Type I Alpha 2 (COL1a2)

kl215Rb51Ⅰ型胶原α2(COL1α2)多克隆抗体Polyclonal Antibody to Collagen Type I Alpha 2 (COL1a2)

kl216Ca01单核细胞趋化蛋白4(MCP4)多克隆抗体Polyclonal Antibody to Monocyte Chemotactic Protein 4 (MCP4)

kl216Eq01单核细胞趋化蛋白4(MCP4)多克隆抗体Polyclonal Antibody to Monocyte Chemotactic Protein 4 (MCP4)

kl216Hu01单核细胞趋化蛋白4(MCP4)多克隆抗体Polyclonal Antibody to Monocyte Chemotactic Protein 4 (MCP4)

kl217Bo01α1-微球蛋白(α1M)多克隆抗体Polyclonal Antibody to Alpha-1-Microglobulin/Bikunin Precursor (a1M)

kl217Gu01α1-微球蛋白(α1M)多克隆抗体Polyclonal Antibody to Alpha-1-Microglobulin/Bikunin Precursor (a1M)

kl217Po01α1-微球蛋白(α1M)多克隆抗体Polyclonal Antibody to Alpha-1-Microglobulin/Bikunin Precursor (a1M)

kl218Bo01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl218Ca01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl218Cp01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl218Ga01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl218Po01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl218Rb51转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl218Si01转化生长因子β2(TGFβ2)多克隆抗体Polyclonal Antibody to Transforming Growth Factor Beta 2 (TGFb2)

kl220Bo01肾上腺髓质素(ADM)多克隆抗体Polyclonal Antibody to Adrenomedullin (ADM)

kl220Ca01肾上腺髓质素(ADM)多克隆抗体Polyclonal Antibody to Adrenomedullin (ADM)

kl220Eq01肾上腺髓质素(ADM)多克隆抗体Polyclonal Antibody to Adrenomedullin (ADM)