磷酸化TRAF2和NCK激酶相互作用蛋白抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化TRAF2和NCK激酶相互作用蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when over expressed in Phoenix-A cells. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing磷酸化TRAF2和NCK激酶相互作用蛋白抗体 protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. Northern analysis indicates TNIK expression in human heart, skeletal muscle, and brain, with lower levels of expression in kidney, liver, lung, and pancreas. ESTs have been isolated from human tissue libraries, including normal amnion, gallbladder and skin.

磷酸化TRAF2和NCK激酶相互作用蛋白抗体Also known as:

TNIK (phospho S764); p-TNIK (phospho S764); TNIK (phospho-Ser764); TNIK (phospho-S764); p-TNIK (Ser764); p-TNIK (S764); Traf2 and NCK interacting kinase; 1500031A17RIK; 4831440I19RIK; AI451411; C530008O15Rik; C630040K21RIK; KIAA0551; MGC189819; MGC189859; RGD1561817; TNIK; TNIK_HUMAN; TRAF2 and NCK-interacting protein kinase.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化TRAF2和NCK激酶相互作用蛋白抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human TNIK around the phosphorylation site of Ser764.

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Predicted Molecular Weight: 150kDa.

磷酸化TRAF2和NCK激酶相互作用蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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