磷酸化白细胞介素1受体衔接蛋白抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化白细胞介素1受体衔接蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The Toll-like receptor (TLR) family in mammals comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, 磷酸化白细胞介素1受体衔接蛋白抗体TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TIRAP (TIR domain-containing adaptor protein) is an adaptor protein used by TLR4. Blocking TIRAP inhibits TLR4-mediated signaling events, including DC maturation and cytokine production.

磷酸化白细胞介素1受体衔接蛋白抗体Also known as:

TIRAP (phospho Y86); Adapter protein wyatt; MAL antibody MyD88 adapter like protein; TIR domain containing adapter protein; Toll interleukin 1 receptor (TIR) domain containing adaptor protein; Toll interleukin 1 receptor domain containing adapter protein; Toll like receptor adaptor protein; Wyatt.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化白细胞介素1受体衔接蛋白抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Dog, Pig, Cow, Horse, Guinea Pig, .

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Immunogen: KLH conjugated Synthesised acetylpeptide derived from human TIRAP around the acetylation site of Tyr86 [KD(p-Y)DV].

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磷酸化白细胞介素1受体衔接蛋白抗体Predicted Molecular Weight: 24kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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