冷”蛋白TRPM8抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 冷”蛋白TRPM8抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.冷”蛋白TRPM8抗体 Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.

冷”蛋白TRPM8抗体Also known as:

LTrpC-6; LTrpC6 antibody Short form of the TRPM8 cationic channel; Transient receptor potential cation channel subfamily M member 8; Transient receptor potential p8; Trp p8; Trp-p8; Trpm8; TRPM8_HUMAN; TRPP8; MGC2849; transient receptor potential-p8; Long transient receptor potential channel 6.

Specificity:

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Rabbit Polyclonal IgG,冷”蛋白TRPM8抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human TRPM8.

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Predicted Molecular Weight: 128kDa.

Storage:

冷”蛋白TRPM8抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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