环指蛋白调节蛋白激酶C蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 环指蛋白调节蛋白激酶C蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Tripartite motif-containing protein 41 (TRIM41), also known as RINCK, is a 630 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. 环指蛋白调节蛋白激酶C蛋白抗体Localized to both the nucleus and cytoplasm, TRIM41 associates with protein kinase C (PKC) through the C1A domain of PKC. Studies have shown that overexpression of TRIM41 reduces the levels of PKC in cells, whereas knockdown of TRIM41 leads to increased levels of PKC. Thus, it is hypothesized that TRIM41 plays a role in regulating PCK levels in cells, specifically through the ubiquitination of PKC. Four isoforms of TRIM41 exist as a result of alternative splicing events.

环指蛋白调节蛋白激酶C蛋白抗体Also known as:

RINCK; RING finger protein that interacts with C kinase; Trim41; Tripartite motif containing 41; TRI41_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human,环指蛋白调节蛋白激酶C蛋白抗体 Mouse, Rat, Dog, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human TRIM41.

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Predicted Molecular Weight: 72kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

环指蛋白调节蛋白激酶C蛋白抗体Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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