供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL9736R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 肿瘤蛋白D53抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The cell commits to dividing during the G2/M phase transition, and the timing of mitotic entry is tightly regulated to guarantee correct chromosome segregation. D53, also referred to as tumor protein D52-like 1 (TPD52L1), is a coiled-coil motif-bearing member of the D52 tumor protein family. D53 intereacts with 14-3-3, a negative regulator of the G2/M 肿瘤蛋白D53抗体transition, in breast cancer cells. Expression of D53 is highly upregulated at the G2/M phase transition in breast cancer cell lines, and deregulated expression of this protein can adversely affect the completion of mitosis. D53 may function as a signaling intermediate and/or regulator of vesicle trafficking and cell proliferation.
肿瘤蛋白D53抗体Also known as:
D53; D54; hD53; hD54; Tpd52l1; TPD52L2 TPD53_HUMAN; Tumor protein D52 like 1; Tumor protein D52 like 2; Tumor protein D52-like 1; Tumor protein D53; Tumor protein D54.
Specificity:
●
Rabbit Polyclonal IgG,肿瘤蛋白D53抗体 affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human TPD52L1/D53.
●
肿瘤蛋白D53抗体Predicted Molecular Weight: 22kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-F=1:100-500 IF=1:50-200
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user
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