破伤风毒素重链抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 破伤风毒素重链抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmi破伤风毒素重链抗体tter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.

破伤风毒素重链抗体Also known as:

Tentoxylysin; Tetanus toxin chain H; Tetanus toxin heavy chain; TETX_CLOTE.

Specificity:

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Rabbit Polyclonal IgG, 破伤风毒素重链抗体affinity purified by Protein A.

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Reacts with: Clostridium tetani E88.

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Immunogen: KLH conjugated synthetic peptide derived from Clostridium tetani E88 Tetanus toxin heavy chain.

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破伤风毒素重链抗体Predicted Molecular Weight: 94kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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