肿瘤血管内皮标志物8抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 肿瘤血管内皮标志物8抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative 肿瘤血管内皮标志物8抗体 agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

 肿瘤血管内皮标志物8抗体Also known as:

Anthrax toxin receptor 1; Anthrax toxin receptor 1 precursor; ANTXR 1; ANTXR1; ATR; TEM-8; TEM 8; TEM8; Tumor Endothelial Marker 8; Tumor endothelial marker 8 precursor; ANTR1_HUMAN; Anthrax toxin receptor-1; FLJ11298; FLJ21776.

Specificity:

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Rabbit Polyclonal IgG,  肿瘤血管内皮标志物8抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human TEM8.

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Predicted Molecular Weight: 59kDa.

Storage:

 肿瘤血管内皮标志物8抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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