跨膜蛋白101抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 跨膜蛋白101抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

TMEM101 is a 257 amino acid protein encoded by a gene that maps to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of跨膜蛋白101抗体  p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dubé syndrome and Canavan disease are also associated with chromosome 17.

跨膜蛋白101抗体 Also known as:

FLJ23987; MGC4251; TM101_HUMAN; NF kappa B activating protein 130; Putative NF kappa B activating protein 130; TMEM101; Transmembrane protein 101.

Specificity:

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Rabbit Polyclonal IgG,跨膜蛋白101抗体  affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human TMEM101.

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Predicted Molecular Weight: 29kDa.

跨膜蛋白101抗体 Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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