环指蛋白88抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 环指蛋白88抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, all of which lack a B-box type 1 domain, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Additional domains C-terminal to the CC region are variably 环指蛋白88抗体 present. Expression of TRIM5 variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. The TRIM5 delta isoform has been shown to colocalize with the topoisomerase I-interacting proteins BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse环指蛋白88抗体  and human cells where it appears to serve as a scaffold for the assembly of endogenous BTBD proteins. TRIM5 delta also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.

Also known as:

EG667823; Gm8833; RING finger protein 88; RNF88; TRIM5; Tripartite motif containing 5 transcript variant iota; Tripartite motif containing 5 transcript variant kappa; Tripartite motif 环指蛋白88抗体 containing protein 5; Tripartite motif protein 5; Tripartite motif protein TRIM5.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human TRIM5 delta.

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环指蛋白88抗体 Predicted Molecular Weight: 27kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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