骨骼肌慢肌肌钙蛋白I抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 骨骼肌慢肌肌钙蛋白I抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and 骨骼肌慢肌肌钙蛋白I抗体thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac 骨骼肌慢肌肌钙蛋白I抗体and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008].

Also known as:

骨骼肌慢肌肌钙蛋白I抗体Troponin I, slow skeletal muscle; SSTNI; TNN1; TNNI1_MOUSE; Troponin I slow skeletal muscle; Troponin I, slow twitch isoform.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human Tnni1.

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Predicted Molecular Weight: 21kDa.

骨骼肌慢肌肌钙蛋白I抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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