TRIM72蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml TRIM72蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM72 (tripartite motif containing 72), also known as MG53, is a 477 amino acid cytoplasmic vesicle membrane protein that belongs to the TRIM/RBCC family. Existing as a homooligomer, TRIM72 contains one B box-type zinc finger, one B30.2/SPRY domain and TRIM72蛋白抗体a RING-type zinc finger. TRIM72 is considered a muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. TRIM72 is required for transport of dysferlin to sites of cell injury during repair patch formation. TRIM72 also regulates membrane budding and exocytosis and may be involved in the regulation ofTRIM72蛋白抗体 the mobility of KV2.1-containing endocytic vesicles. TRIM72 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 16p11.2.

TRIM72蛋白抗体Also known as:

LOC493829; Mg53; Mitsugumin-53; TRI72_HUMAN; trim72; Tripartite motif containing 72; Tripartite motif containing protein 72; Tripartite motif-containing protein 72.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human TRIM72.

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Predicted Molecular Weight: 53kDa.

TRIM72蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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