微管蛋白特定伴侣蛋白E抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 微管蛋白特定伴侣蛋白E抗体  Buffer = Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Background:

Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCE (tubulin folding cofactor E),微管蛋白特定伴侣蛋白E抗体 also known as HRD, KCS, KCS1 or pac2, is a 527 amino acid cytoplasmic protein containing one CAP-Gly domain and seven LRR (leucine-rich) repeats. TBCE is involved in the second step of the Tubulin folding pathway and is implicated in the maintenance of the neuronal microtubule network. TBCE associates with microtubules and proteasomes, and protects against misfolded protein stress. Mutations in the gene encoding TBCE are the cause of hypoparathyroidism-retardation-dysmorphism syndrome and Kenny-Caffey syndrome type 1.

微管蛋白特定伴侣蛋白E抗体Also known as:

HRD; KCS; KCS1; Pac2; tbce; TBCE_HUMAN; Tubulin specific chaperone e; Tubulin-folding cofactor E; Tubulin-specific chaperone E.

Specificity:

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Rabbit Polyclonal IgG, 微管蛋白特定伴侣蛋白E抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human TBCE.

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Predicted Molecular Weight: 59kDa.

微管蛋白特定伴侣蛋白E抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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