UL16结合蛋白1蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml UL16结合蛋白1蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

N2DL1 is a human rat mouse ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionUL16结合蛋白1蛋白抗体  pathway. The interaction with UL16 blocks the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.UL16结合蛋白1蛋白抗体  ULBP1 is expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues.

Also known as:

ALCAN-beta; N2DL-1; N2DL1; NKG2D ligand 1 precursor; NKG2DL1; RAET1I; Retinoic acid early transcript 1I; UL16; UL16结合蛋白1蛋白抗体 UL16 binding protein 1; UL16-binding protein 1; N2DL1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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UL16结合蛋白1蛋白抗体 Immunogen: KLH conjugated synthetic peptide derived from human ULBP1.

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Predicted Molecular Weight: 25kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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