磷酸化信号淋巴细胞活化分子CD150抗体

Quantity size:

0.1ml

Concentration:

1mg/ml磷酸化信号淋巴细胞活化分子CD150抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

SLAM, a novel glycoprotein of 37kDa, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells 磷酸化信号淋巴细胞活化分子CD150抗体after activation. Activated B cells express the membrane bound form of SLAM and the soluble and cytoplasmic isoforms of SLAM, and the expression levels of membrane bound SLAM on B cells are rapidly regulated after activation in vitro. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interaction磷酸化信号淋巴细胞活化分子CD150抗体s enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells.

Also known as:

SLAMF1(phospho Y281); CD150 antigen; Cdw150; Estm51; Ipo 3; Ipo3; MGC151472; MGC151476; Signaling lymphocytic activation molecule; Signaling lymphocytic activation molecule family member 1; Signaling lymphocytic activation molecule precursor; Slaf1;磷酸化信号淋巴细胞活化分子CD150抗体 SLAM family, member 1; Slamf; Slamf1; SLAMF1 protein.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human SLAMF1 around 磷酸化信号淋巴细胞活化分子CD150抗体the phosphorylation site of Tyr281.

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Predicted Molecular Weight: 35kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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