| 供货周期： | 现货 |
| 品牌： | 康朗生物 |
| 规格： | 0.1ml/0.2ml |
| 货号： | KL20432R |
| CAS号： |
Quantity size:
0.2ml
Concentration:
1mg/ml 肌营养不良蛋白相关蛋白1抗体 Buffer = Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Background:
Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been 肌营养不良蛋白相关蛋白1抗体speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.
肌营养不良蛋白相关蛋白1抗体Also known as:
DMDL; DRP 1; DRP; DRP-1; DRP1; Dystrophin like protein; Dystrophin related protein 1; Dystrophin related protein; Dystrophin-related protein 1; FLJ23678; UTRN; UTRO_HUMAN; Utrophin (homologous to dystrophin); Utrophin
Specificity:
●
Rabbit Polyclonal IgG肌营养不良蛋白相关蛋白1抗体, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Utrophin.
肌营养不良蛋白相关蛋白1抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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