T淋巴细胞负调节蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml T淋巴细胞负调节蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

T cell activation by APCs is positively and negatively regulated by members of the B7 family. We have identified a previously unknown function for B7 familyrelated protein V-set and Ig domaincontaining 4 (VSIG4). Administration to mice of soluble VSIG4-Ig fusion molecules reduced the induction of T cell responses in vivo and inhibited the production of Th celldependent IgG T淋巴细胞负调节蛋白抗体 responses. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophagesT淋巴细胞负调节蛋白抗体  and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.

Also known as:

T淋巴细胞负调节蛋白抗体 V-set and immunoglobulin domain-containing protein 4; CRIg; V set and immunoglobulin domain containing 4; Z39IG; VSIG4_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, .

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Immunogen: KLH conjugated synthetic peptide derived from human VSIG4 Isoform 3.

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Predicted Molecular Weight: 33kDa.

T淋巴细胞负调节蛋白抗体 Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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