磷酸化鸟苷酸转换因子VAV1抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化鸟苷酸转换因子VAV1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation.磷酸化鸟苷酸转换因子VAV1抗体 The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012].

磷酸化鸟苷酸转换因子VAV1抗体Also known as:

VAV1(phospho Y174); Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN; VAV1.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化鸟苷酸转换因子VAV1抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human VAV1 around the phosphorylation site of Tyr174.

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磷酸化鸟苷酸转换因子VAV1抗体Predicted Molecular Weight: 98kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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