血管假性血友病因子/血管性血友病因子抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 血管假性血友病因子/血管性血友病因子抗体  Buffer = Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Background:

Von Willebrand Factor (VWF) was previously known as Factor VIII related antigen. VWF is synthesized exclusively by endothelial cells and megakaryocytes, and stored in the intracellular granules or constitutively secreted into plasma. This glycoprotein functions as both an antihemophilic factor carrier and a platelet vessel wall mediator in the blood coagulation 血管假性血友病因子/血管性血友病因子抗体system. Important in the maintenance of homeostasis, it participates in platelet vessel wall interactions by forming a noncovalent complex with coagulation factor VIII at the site of vascular injury. The Von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. Mutations in this gene or deficiencies in this protein result in Von Willebrand's disease. VWD is characterized by frequent bleeding (gingival, minor skin quantitative lacerations, menorrhagia, etc.).

血管假性血友病因子/血管性血友病因子抗体Also known as:

Von Willebrand Factor; Coagulation factor VIII; F8VWF; Factor VIII related antigen; von Willebrand antigen 2; Von Willebrand antigen II; Von Willebrand disease; VWD; VWF; VWF_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,血管假性血友病因子/血管性血友病因子抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human VWF.

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Predicted Molecular Weight: 309kDa.

Storage:

血管假性血友病因子/血管性血友病因子抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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