包含氧化还原酶的WW域抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 包含氧化还原酶的WW域抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate.包含氧化还原酶的WW域抗体 This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this 包含氧化还原酶的WW域抗体gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]

Also known as:

包含氧化还原酶的WW域抗体D16S432E; FOR; FOR II protein; FRA16D; Fragile 16D oxido reductase; fragile site FRA16D oxidoreductase; HHCMA 56; HHCMA56; PRO0128; putative oxidoreductase; WOX 1; WOX1; WW domain containing oxidoreductase; WW domain-containing protein WWOX; WWOX2; WWOX4; WWOX8; WWOX.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human WWOX.

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Predicted Molecular Weight: 46kDa.

包含氧化还原酶的WW域抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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