RAN结合蛋白3抗体_价格_上海联迈生物工程有限公司

产品详情

RAN结合蛋白3抗体

英文名称 RanBP3

中文名称 RAN结合蛋白3抗体

别名 Ran BP-3; Ran binding protein 3; Ran-binding protein 3; RANB3_HUMAN; RanBP3.

研究领域细胞生物信号转导细胞周期蛋白细胞分化表观遗传学

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig,

产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 60kDa

细胞定位细胞核细胞浆

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human RanBP3:441-540/567

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.

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供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM20113R
CAS号：